Radiosurgery for treatment of brain metastases: Estimation of patient eligibility using three stratification systems

作者: José Lorenzoni , Daniel Devriendt , Nicolas Massager , Phillippe David , Salvador Ruíz

DOI: 10.1016/J.IJROBP.2004.02.017

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摘要: Abstract Purpose To compare three patient stratification systems predicting survival: recursive partitioning analysis (RPA), score index for radiosurgery in brain metastases (SIR), and a proposed basic (BS-BM). Methods materials We analyzed the outcome of 110 patients treated with Leksell Gamma Knife between December 1999 January 2003. The BS-BM was calculated by evaluating main prognostic factors: Karnofsky performance status, primary tumor control, presence extracranial metastases. Results median survival 27.6 months RPA Class I, 10.7 II, 2.8 III ( p = 0.031 0.043, respectively). Conclusion SIR were most accurate estimating survival. They specific enough to identify short (SIR 0–3 0). Because it simplicity, is easier use.

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