Choroid plexus tumours.

作者: J E A Wolff , M Sajedi , R Brant , M J Coppes , R M Egeler

DOI: 10.1038/SJ.BJC.6600609

关键词:

摘要: Choroid plexus tumours are rare epithelial brain and limited information is available regarding their biology the best treatment. A meta-analysis was done to determine prognostic factors influence of various treatment modalities. thorough review medical literature (1966–1998) revealed 566 well-documented choroid tumours. These were entered into a database, which analysed Most patients with supratentorial tumour children, while most common sites in adults fourth ventricle cerebellar pontine angle. Cerebellar angle more frequently benign. Histology important factor, as one, five, 10-year projected survival rates 90, 81, 77% plexus-papilloma (n=353) compared only 71, 41, 35% plexus-carcinoma respectively (P<0.0005). Surgery prognostically relevant for both (P=0.0005) (P=0.0001). Radiotherapy associated significantly better plexus-carcinomas. Eight 22 documented plexus-carcinomas responded chemotherapy. Relapse after primary poor factor but not patients. Treatment should start radical surgical resection. This be followed by adjuvant case plexus-carcinoma, ‘wait see’ approach plexus-papilloma. British Journal Cancer (2002) 87, 1086–1091. doi:10.1038/sj.bjc.6600609 www.bjcancer.com © 2002 Research UK

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