Muir-Torre syndrome-associated pleomorphic liposarcoma arising in a previous radiation field
作者： Masato Yozu , Pennie Symmans , Michael Dray , Jennifer Griffin , Catherine Han
DOI: 10.1007/S00428-012-1369-X
关键词:
摘要: Muir-Torre syndrome is a variant of Lynch syndrome, characterised by sebaceous neoplasia and/or keratoacanthomas associated with visceral malignancies. caused germline mutations one the mismatch repair genes, frequently MSH2 and less MLH1 MSH6. Visceral malignancies include colorectal, endometrial other gastrointestinal, urological gynaecological Small numbers syndrome-associated soft tissue sarcomas have been reported, but there are no reported cases in syndrome. In this study, we report 74-year-old man known confirmed mutation, diagnosed pleomorphic liposarcoma right buttock previous radiation field. The tumour showed loss expression MSH6 on immunohistochemistry. Immunohistochemistry another different patient history or proteins. This first sarcoma case post-radiation
springer.com
sci-hub.se 参考文章(23)
William G. Cahan, Helen Q. Woodard, Norman L. Higinbotham, Fred W. Stewart, Bradley L. Coley, Sarcoma arising in irradiated bone Cancer. ,vol. 82, pp. 8- 34 ,(1998) , 10.1002/(SICI)1097-0142(19980101)82:1<8::AID-CNCR3>3.0.CO;2-W
H. F.A. Vasen, A. Stormorken, F. H. Menko, F. M. Nagengast, J. H. Kleibeuker, G. Griffioen, B. G. Taal, P. Moller, J. T. Wijnen, MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers : A study of hereditary nonpolyposis colorectal cancer families Journal of Clinical Oncology. ,vol. 19, pp. 4074- 4080 ,(2001) , 10.1200/JCO.2001.19.20.4074
William G. Cahan, Helen Q. Woodard, Norman L. Higinbotham, Fred W. Stewart, Bradley L. Coley, Sarcoma in irradiated bone. Report of eleven cases Cancer. ,vol. 1, pp. 3- 29 ,(1948) , 10.1002/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7
Keiji Hirata, Shuichi Kanemitsu, Yoshifumi Nakayama, Naoki Nagata, Hideaki Itoh, Hideo Ohnishi, Hideki Ishikawa, Yoichi Furukawa, , A novel germline mutation of MSH2 in a hereditary nonpolyposis colorectal cancer patient with liposarcoma. The American Journal of Gastroenterology. ,vol. 101, pp. 193- 196 ,(2006) , 10.1111/J.1572-0241.2005.00308.X
Mef Nilbert, Christina Therkildsen, Anja Nissen, Måns Åkerman, Inge Bernstein, Sarcomas associated with hereditary nonpolyposis colorectal cancer: broad anatomical and morphological spectrum. Familial Cancer. ,vol. 8, pp. 209- 213 ,(2009) , 10.1007/S10689-008-9230-8
E. Robinson, A. I. Neugut, P. Wylie, Clinical aspects of postirradiation sarcomas. Journal of the National Cancer Institute. ,vol. 80, pp. 233- 240 ,(1988) , 10.1093/JNCI/80.4.233
M A den Bakker, C Seynaeve, M Kliffen, W N M Dinjens, Microsatellite instability in a pleomorphic rhabdomyosarcoma in a patient with hereditary non-polyposis colorectal cancer. Histopathology. ,vol. 43, pp. 297- 299 ,(2003) , 10.1046/J.1365-2559.2003.01681.X
Angela Brieger, Knut Engels, Dieter Schaefer, Guido Plotz, Stefan Zeuzem, Jochen Raedle, Joerg Trojan, Malignant fibrous histiocytoma is a rare Lynch syndrome-associated tumor in two German families. Familial Cancer. ,vol. 10, pp. 591- 595 ,(2011) , 10.1007/S10689-011-9455-9
Norio Azumi, Jeffrey Curtis, Richard L. Kempson, Michael R. Hendrickson, Atypical and malignant neoplasms showing lipomatous differentiation. A study of 111 cases The American Journal of Surgical Pathology. ,vol. 11, pp. 161- 183 ,(1987) , 10.1097/00000478-198703000-00001
Katsuyasu Suwa, Masaki Ohmori, Hiroshi Miki, Microsatellite alterations in various sarcomas in Japanese patients. Journal of Orthopaedic Science. ,vol. 4, pp. 223- 230 ,(1999) , 10.1007/S007760050097