PI3K inhibitor combined with miR-125b inhibitor sensitize TMZ-induced anti-glioma stem cancer effects through inactivation of Wnt/β-catenin signaling pathway.
作者： Lei Shi , Xifeng Fei , Zhimin Wang , Yongping You
DOI: 10.1007/S11626-015-9931-X
关键词:
摘要: … Temozolomide (TMZ) is a promising chemotherapeutic agent … , and postoperative recurrence and multiple drug resistance (… of TMZ, miR-125b inhibitor, and PI3K inhibitor on the invasion …
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sci-hub.se 参考文章(23)
Chuanlu Jiang, LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway. Molecular Medicine Reports. ,vol. 5, pp. 575- 579 ,(2011) , 10.3892/MMR.2011.674
Fei Wang, Weizhong Xiao, Jiyong Sun, Donghua Han, Youhou Zhu, MiRNA-181c inhibits EGFR-signaling-dependent MMP9 activation via suppressing Akt phosphorylation in glioblastoma Tumor Biology. ,vol. 35, pp. 8653- 8658 ,(2014) , 10.1007/S13277-014-2131-6
Lei Shi, Zhimin Wang, Guan Sun, Curcumin induces glioma stem-like cell formation NeuroReport. ,vol. 26, pp. 167- 172 ,(2015) , 10.1097/WNR.0000000000000320
Ke Sai, Wen-Yu Li, Yin-Sheng Chen, Jian Wang, Su Guan, Qun-Ying Yang, Cheng-Cheng Guo, Yong-Gao Mou, Wei-Ping Li, Zhong-Ping Chen, Triptolide Synergistically Enhances Temozolomide-Induced Apoptosis and Potentiates Inhibition of NF-κB Signaling in Glioma Initiating Cells The American Journal of Chinese Medicine. ,vol. 42, pp. 485- 503 ,(2014) , 10.1142/S0192415X14500323
Lei Shi, Yi Wan, Guan Sun, Shuguang Zhang, Zhimin Wang, Yanjun Zeng, miR-125b Inhibitor May Enhance the Invasion-Prevention Activity of Temozolomide in Glioblastoma Stem Cells by Targeting PIAS3 BioDrugs. ,vol. 28, pp. 41- 54 ,(2014) , 10.1007/S40259-013-0053-2
Ryan J. Atkins, James Dimou, Lucy Paradiso, Andrew P. Morokoff, Andrew H. Kaye, Katharine J. Drummond, Christopher M. Hovens, Regulation of glycogen synthase kinase-3 beta (GSK-3β) by the Akt pathway in gliomas Journal of Clinical Neuroscience. ,vol. 19, pp. 1558- 1563 ,(2012) , 10.1016/J.JOCN.2012.07.002
Yi Wan, Guan Sun, Shuguang Zhang, Zhimin Wang, Lei Shi, MicroRNA-125b inhibitor sensitizes human primary glioblastoma cells to chemotherapeutic drug temozolomide on invasion In Vitro Cellular & Developmental Biology – Animal. ,vol. 49, pp. 599- 607 ,(2013) , 10.1007/S11626-013-9644-Y
Mian Guo, Xiaoming Zhang, Guangzhi Wang, Jiahang Sun, Zhenfeng Jiang, Kevork Khadarian, Shan Yu, Yan Zhao, Chuncheng Xie, Kelvin Zhang, Minwei Zhu, Hong Shen, Zhiguo Lin, Chuanlu Jiang, Jia Shen, Yongri Zheng, miR-603 promotes glioma cell growth via Wnt/β-catenin pathway by inhibiting WIF1 and CTNNBIP1. Cancer Letters. ,vol. 360, pp. 76- 86 ,(2015) , 10.1016/J.CANLET.2015.02.003
Jian Chen, Xingli Fu, Yi Wan, Zhimin Wang, Dongyi Jiang, Lei Shi, miR-125b inhibitor enhance the chemosensitivity of glioblastoma stem cells to temozolomide by targeting Bak1 Tumor Biology. ,vol. 35, pp. 6293- 6302 ,(2014) , 10.1007/S13277-014-1821-4
M. Mendiburu-Eliçabe, J. Gil-Ranedo, M. Izquierdo, Efficacy of rapamycin against glioblastoma cancer stem cells Clinical & Translational Oncology. ,vol. 16, pp. 495- 502 ,(2014) , 10.1007/S12094-013-1109-Y