Methicillin-resistant Staphylococcus aureus (MRSA) in the community - laboratory based study

摘要: Objective To determine the occurrence and antibiotic resistanceof community-acquired methicillin-resistant Staphylococcusaureus (MRSA) isolates. Methods used In 2003-2005,consecutive samples of nasal, throat, eye, ear genitourinarytract swabs, swabs wound infections soft skintissue sputum obtained from outpatientssubmitted to Laboratory with clinical indicationswere analyzed for presence Staphylococcus aureus. Thedisc diffusion method using Mueller-Hinton agar (Oxoid,Besingstoke, UK) was test against nine antimicrobials.Oxacillin-resistance confirmed by E-test (AB Biodisc,Solna, Sweden). Results A total 1583 (11.3%) nonduplicateS. aureus isolated 13 937 samples. MRSA detectedin 63 (4.1%) S. isolates more frequentlyfrom infected genitourinary tract wounds thanother sites (p<0.0001). The patients in both age groups ≥65and 0-6 years were frequently withMRSA than other (p=0.02). Statisticallysignificant differences susceptibility rates betweenMSSA found all tested(p=0.0053 p<0.000). frequentlymultidrug resistant (MDR) MSSA (p=0.0009).SCCmec type IV or V phenotype detected 30 (47.6%) ofMRSA Conclusion Although low prevalencewas noted, SCCmec IV/V phenotypesin community is particular concern. Effective controlof dissemination throughout willlikely require effective control monitoring nosocomialMRSA transmission