Sleep in the neurological intensive care unit: feasibility of quantifying sleep after melatonin supplementation with environmental light and noise reduction.

摘要: Purpose Sleep deprivation may be particularly detrimental to intensive care unit (ICU) patients. Polysomnography has demonstrated abnormal sleep in medical and surgical ICU populations. Both environmental factors circadian disruption have been implicated. We hypothesized that patients a neurologic would demonstrate similar disturbances combination of sleep-promoting interventions increase time. Methods Twelve were enrolled this pilot-randomized, controlled, study ICU. For adult undergoing continuous EEG for clinical purposes, noise-cancelling headphones eye masks worn, an oral dose melatonin was administered 3 days, or until stopped. scored according standard criteria; characterized analyzed quantitatively. Results Sixty-five percent the patients' recordings unscorable based on accepted standardized therefore, measures could not compared. those with scored, total time normal, although fragmented spent slow-wave rapid movement notably decreased. Patients had worse injury severity measures, absent significantly slower posterior dominant rhythm, less coherence faster frequencies. Clinical outcomes between intervention control groups. Conclusions Although feasible, quantification currently criteria limited ability score sleep. Similar other ICUs, is abnormal; sleep-like states greater severity. This by strict enrollment criteria. A reliable method quantify needed.