Pathogenesis of intracranial germ cell tumors reconsidered

作者: Keiji Sano

DOI: 10.3171/JNS.1999.90.2.0258

关键词:

摘要: Object. To determine the pathogenesis of intracranial germ cell tumors (GCTs), author studied 153 cases these encountered through 1994, 62.7% which showed monotypic histological patterns and 37.3% were shown to be mixed tumors. Methods. Six patients died soon after admission underwent autopsy; other surgery followed by radio- and/or chemotherapy. One hundred thirty-four end 1997. All with a choriocarcinoma within 1 year. Patients yolk sac tumor (endodermal sinus tumor) or an embryonal carcinoma also had poor outcomes. mature teratoma 5- 10-year survival rates 93% each. immature 86% each, whereas who malignant transformation 3-year rate 50%. germinoma 5-year 96% 93%. These results may bring into ...

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