Regression analysis of prognostic factors in colorectal cancer after curative resections

摘要: The clinical, laboratory, and pathologic data of 310 patients who had curative resections were prospectively collected analyzed in a multiple step wise regression model. Although several factors (i.e., venous invasion) importance univariate analysis, the following conclusions reflect outcome relative analysis only. Blood loss as an initial symptom duration symptoms associated with better prognosis. Location primary tumor, age, sex did not appear to have prognostic value. Observations during operation such palpable lymph nodes, fixity adjacent organs, tumor spill related diminished tumor-free survival. Laboratory (hemoglobin, leukocytes, ESR, GGTP, SGOT, SGPT, LDH, total protein, CEA) tested for their potential values. Only preoperative low protein level or elevated CEA increased risk death due recurrent tumor. histopathologic features (stage grade), exception invasion, determination aforementioned variables can be included index on base which high-risk groups suitable adjuvant studies identified.