Finite-Element Modelling of Biotransistors.

摘要: Current research efforts in biosensor design attempt to integrate biochemical assays with semiconductor substrates and microfluidic assemblies realize fully integrated lab-on-chip devices. The DNA biotransistor (BioFET) is an example of such a device. process chemical modification the FET attachment linker probe molecules statistical that can result variations sensed signal between different BioFET cells array. In order quantify these other assess their importance design, complete physical simulation device necessary. Here, we perform mean-field finite-element modelling short channel, two-dimensional We compare results this model one-dimensional calculation show important differences, illustrating molecular structure, placement conformation determining output signal.