The complexity of p53 modulation: emerging patterns from divergent signals

作者: A. J. Giaccia , M. B. Kastan

DOI: 10.1101/GAD.12.19.2973

关键词:

摘要: Functional inactivation of p53 by gene mutation and deletion, protein degradation, or viral oncogene binding renders a mammalian cell susceptible to oncogenic stimuli and …

参考文章(111)
Stanton C Goldman, Chaw-Yaun Chen, Timothy J Lansing, Tona M Gilmer, Michael B Kastan, None, The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localization. American Journal of Pathology. ,vol. 148, pp. 1381- 1385 ,(1996)
Mats Ljungman, Fenfen Zhang, BLOCKAGE OF RNA POLYMERASE AS A POSSIBLE TRIGGER FOR U.V. LIGHT-INDUCED APOPTOSIS Oncogene. ,vol. 13, pp. 823- 831 ,(1996)
N Goldfinger, V Rotter, D Schwartz, Expression of p53 protein in spermatogenesis is confined to the tetraploid pachytene primary spermatocytes Oncogene. ,vol. 8, pp. 1487- 1494 ,(1993)
Matthew J. F. Waterman, Elena S. Stavridi, Jennifer L. F. Waterman, Thanos D. Halazonetis, ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins Nature Genetics. ,vol. 19, pp. 175- 178 ,(1998) , 10.1038/542
Richard A. Woo, Kevin G. McLure, Susan P. Lees-Miller, Derrick E. Rancourt, Patrick W. K. Lee, DNA-dependent protein kinase acts upstream of p53 in response to DNA damage Nature. ,vol. 394, pp. 700- 704 ,(1998) , 10.1038/29343
N L Lill, M J Tevethia, R Eckner, D M Livingston, N Modjtahedi, p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen. Journal of Virology. ,vol. 71, pp. 129- 137 ,(1997) , 10.1128/JVI.71.1.129-137.1997
Amato J. Giaccia, Constantinos Koumenis, Donna M. Peehl, Theodore Girinsky, Thomas G. Graeber, Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents. Cancer Research. ,vol. 55, pp. 3726- 3731 ,(1995)
Wei Gu, Xiao-Lu Shi, Robert G. Roeder, Synergistic activation of transcription by CBP and p53 Nature. ,vol. 387, pp. 819- 823 ,(1997) , 10.1038/42972
Nancy L. Lill, Steven R. Grossman, Doron Ginsberg, James DeCaprio, David M. Livingston, Binding and modulation of p53 by p300/CBP coactivators Nature. ,vol. 387, pp. 823- 827 ,(1997) , 10.1038/42981
Øystein W. Rønning, Erik O. Pettersen, Niels O. Juul, Regulation of protein metabolism of human cells during and after acute hypoxia. Cancer Research. ,vol. 46, pp. 4346- 4351 ,(1986)