Metastatic Solid-pseudopapillary Tumour of the Pancreas: Clinico-biological Correlates and Management

摘要: Solid-pseudopapillary tumour of the pancreas is a rare neoplasm young women, currently categorised in World Health Organization classification under exocrine pancreatic tumours. Increased awareness this condition correlated recently with an apparent rise incidence as well recognition more aggressive clinical courses. We describe two patients solid-pseudopapillary pancreas. A smaller, localised unusually white man was surgically excised no evidence recurrence after 2 years. The other case also had uncommon presentation, course resulting vascular encasement superior mesenteric bundle and aorta, local involvement lymph nodes. literature review carried out, main clinico-pathological features strategies treatment are presented. Pathological, genetic molecular distinguish tumours from ductal adenocarcinoma. Furthermore, neuroendocrine differentiation can be found focally occasional cases tumour. Patients disease usually cured by surgery. Prolonged survival seen presence distant metastasis, if such lesions resected surgically. Chemotherapy radiation therapy used when resection not possible. No current chemotherapy regimens considered standard rational protocol for needs to consider its origin behaviour. However, indolent progression similar that