作者: Ivan Berlin , Henian Chen , Lirio S. Covey
DOI: 10.1111/J.1360-0443.2010.03109.X
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摘要: Aims The effect of successful and unsuccessful smoking cessation on depressive mood, anxiety- suicide-related outcomes is unclear. aim this secondary analysis was to explore the relationship between abstinence status these outcomes. Design Cohort adult smokers attempting stop smoking. Smoking assessed by a daily diary; depressed anxiety suicidal tendencies Hamilton Depression Rating Scale (HDRS). association complete point-prevalence with HDRS variables using multi-level linear regression models. Setting Randomized trial sertraline versus placebo for weekly behavioural support provided in clinic. Participants A total 133 past major depression. Findings Pre-quit mood scores did not predict post-quit day. Both continuous abstainers had significantly lower HDRS, suicide scores, adjusted all potential confounders, during period following quit day than non-abstainers who experienced significant deterioration. There but abstinence. Conclusions Contrary expectation, among history depression lead increase depression, or ideation; however, failed attempts did. Persisting attempt while unable achieve may be associated