Granulocytotoxic antibodies in a patient with propylthiouracil-induced agranulocytosis
作者： M. M. Guffy
DOI: 10.1001/ARCHINTE.144.8.1687
关键词:
摘要: • Agranulocytosis developed in a patient who was receiving propylthiouracil. Using microgranulocytotoxicity assay, serum taken from the shown to be strongly granulocytotoxic when tested against patient's granulocytes and those obtained two of eight normal subjects. Tests for granulocyte agglutinins lymphocytotoxicity were negative. Granulocytotoxic activity decreased as peripheral count recovered. Cytotoxicity mediated by complement-dependent IgM antibody.
ama-assn.org
sci-hub.se 参考文章(12)
Michael H. Rosove, Agranulocytosis and antithyroid drugs. Western Journal of Medicine. ,vol. 126, pp. 339- 343 ,(1977)
JS Thompson, JM Herbick, LW Klassen, CD Severson, VL Overlin, JW Blaschke, MA Silverman, CL Vogel, Studies on levamisole-induced agranulocytosis Blood. ,vol. 56, pp. 388- 396 ,(1980) , 10.1182/BLOOD.V56.3.388.BLOODJOURNAL563388
FATAL AGRANULOCYTOSIS DURING TREATMENT OF TOXIC GOITER WITH PROPYLTHIOURACIL Annals of Internal Medicine. ,vol. 34, pp. 1035- 1040 ,(1951) , 10.7326/0003-4819-34-4-1035
Orlando J. Martelo, Bone Marrow Aplasia Following Propylthiouracil Therapy Archives of Internal Medicine. ,vol. 120, pp. 587- 590 ,(1967) , 10.1001/ARCHINTE.1967.00300040071012
Frans H.J. Claas, Janneke Langerak, Jon J. van Rood, Drug-induced antibodies with restricted specificity Immunology Letters. ,vol. 2, pp. 323- 326 ,(1981) , 10.1016/0165-2478(81)90027-4
DAVID S. COOPER, Agranulocytosis Associated with Antithyroid Drugs Annals of Internal Medicine. ,vol. 98, pp. 26- 29 ,(1983) , 10.7326/0003-4819-98-1-26
SigmundA. Weitzman, ThomasP. Stossel, Drug-induced immunological neutropenia. The Lancet. ,vol. 311, pp. 1068- 1072 ,(1978) , 10.1016/S0140-6736(78)90915-7
V. L. Overlin, J. M. Herbick, C. D. Severson, F. H. J. Claas, J. D. 'Amaro, C. P. Burns, R. G. Strauss, J. A. Koepke, J. S. Thompson, New Granulocyte Antigens Demonstrated by Microgranulocytotoxicity Assay Journal of Clinical Investigation. ,vol. 65, pp. 1431- 1439 ,(1980) , 10.1172/JCI109807
Elmer C. Bartels, Agranulocytosis during propylthiouracil therapy The American Journal of Medicine. ,vol. 5, pp. 48- 52 ,(1948) , 10.1016/0002-9343(48)90008-4
EM Berkman, JB Orlin, J Wolfsdorf, An anti-neutrophil antibody associated with a propylthiouracil-induced lupus-like syndrome. Transfusion. ,vol. 23, pp. 135- 138 ,(1983) , 10.1046/J.1537-2995.1983.23283172851.X