Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling.
作者： Giovanni Cuda , Roberto Paternò , Roberto Ceravolo , Mafalda Candigliota , Nicola Perrotti
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摘要: Background— Reactive oxygen species play a critical role in inducing apoptosis. The small GTPase p21 Ras and the ERK1/2 MAPK have been proposed as key regulators of signaling cascade triggered ...
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Alan Eastman, Terrance A. Stadheim, Helen Xiao, Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells. Cancer Research. ,vol. 61, pp. 1533- 1540 ,(2001)
John L. Cleveland, Michael B. Kastan, Cancer. A radical approach to treatment. Nature. ,vol. 407, pp. 309- 311 ,(2000) , 10.1038/35030277
E. Pennisi, Superoxides Relay Ras Protein's Oncogenic Message Science. ,vol. 275, pp. 1567- 1568 ,(1997) , 10.1126/SCIENCE.275.5306.1567
Dafna Bar-Sagi, Alan Hall, Ras and Rho GTPases - A Family Reunion Cell. ,vol. 103, pp. 227- 238 ,(2000) , 10.1016/S0092-8674(00)00115-X
Dietmar Kültz, Samira Madhany, Maurice B. Burg, Hyperosmolality Causes Growth Arrest of Murine Kidney Cells INDUCTION OF GADD45 AND GADD153 BY OSMOSENSING VIA STRESS-ACTIVATED PROTEIN KINASE 2 Journal of Biological Chemistry. ,vol. 273, pp. 13645- 13651 ,(1998) , 10.1074/JBC.273.22.13645
Z. Xia, M. Dickens, J. l Raingeaud, R. J. Davis, M. E. Greenberg, Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis Science. ,vol. 270, pp. 1326- 1331 ,(1995) , 10.1126/SCIENCE.270.5240.1326
Tony Magee, Chris Marshall, New insights into the interaction of Ras with the plasma membrane. Cell. ,vol. 98, pp. 9- 12 ,(1999) , 10.1016/S0092-8674(00)80601-7
Mariarosaria Santillo, Paolo Mondola, Rosalba Serù, Tiziana Annella, Silvana Cassano, Ilaria Ciullo, Mario F. Tecce, Giuseppe Iacomino, Simona Damiano, Giovanni Cuda, Roberto Paternò, Valeria Martignetti, Evelina Mele, Antonio Feliciello, Enrico V. Avvedimento, Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals. Current Biology. ,vol. 11, pp. 614- 619 ,(2001) , 10.1016/S0960-9822(01)00159-2
Ian A. Prior, Angus Harding, Jun Yan, Judith Sluimer, Robert G. Parton, John F. Hancock, GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nature Cell Biology. ,vol. 3, pp. 368- 375 ,(2001) , 10.1038/35070050
Zhongfa Yan, Ming-xing Chen, Manuel Perucho, Eileen Friedman, Oncogenic Ki-ras but Not Oncogenic Ha-rasBlocks Integrin β1-Chain Maturation in Colon Epithelial Cells Journal of Biological Chemistry. ,vol. 272, pp. 30928- 30936 ,(1997) , 10.1074/JBC.272.49.30928