Concordant expression of tissue factor and class II MHC antigens in human placental endothelium

摘要: Summary Villitis of unestablished etiology is a placental lesion frequently associated with high risk pregnancies: it also found in placentae from normal term pregnancies. The the unknown. Vasculitis and thrombosis have been described villitis areas We asked if fetal stem vessel endothelium lesions expresses MHC class II antigens, this thrombogenic activity these vessels. that vessels was usually (HLA-DR, DP DQ) reactive. Reactivity for antigens presence tissue factor reactivity absence thrombomodulin reactivity. These changes on endothelial plasma membranes can promote intravascular coagulation, ischemic necrosis, vasculitis other histological characteristic villitis.