F-18 FDG PET/CT of a Gastric Schwannoma

摘要: Schwannomas, also known as neurilemmomas, are tumors originating from nervous tissue; they have Schwann cell sheaths. According to a recent classification, about 80% of gastrointestinal mesenchymal stromal (GISTs) [1]. Gastrointestinal (GI) schwannomas been reported represent only 3% all GI [2]. These make up 0.2% gastric neoplasms [3]. Schwannomas the tract distinctive conventional that arise in soft tissue or central system. hypothesized myenteric plexus within wall. usually benign, slow-growing, and asymptomatic, therefore most discovered incidentally [3]. The differentiation other submucosal is very difficult. The main differential diagnosis for mass arising wall gastointestinal GIST, which potentially malignant tumor arises interstitial cells Cajal, help regulate peristalsis [4]. diagnostic determination requires positive histological tests S-100 protein vimentin, but negative smooth muscle actin c-KIT. In contrast, GISTs c-KIT can be if located small bowel [5]. Because patients with excellent prognoses, surgical removal sufficient treatment. Gastric normally transformation extremely rare [6]. However, current case (Figs. 1 ​and2)2) illustrates these may exhibit avid F-18 FDG uptake. It remains unclear why high uptake found benign such schwannomas. neural variable frequently high, possibly due over-expression glucose transporter by cells. particular, type 3 human tissues major on neuronal surface [7, 8]. purposes, intense does not distinguish GISTs, data suggest PET limited value preoperative technique assessment schwannoma versus GIST. Fig. 1 A 58-year-old woman was admitted evaluation treatment had previously detected cancer-screening endoscopy. Endoscopy revealed ulcer its surface. Contrast-enhanced CT showed ... Fig. 2 On gross inspection, an 8 × 7 × 6 cm sized well-encapsulated ovoid, firm stomach A mucosal ulceration (2 × 1.5 cm) noted. cut surfaces ...