RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals

作者: Phillip D Zamore , Thomas Tuschl , Phillip A Sharp , David P Bartel

DOI: 10.1016/S0092-8674(00)80620-0

关键词:

摘要: … , we examined the molecular mechanism underlying RNAi. We find that RNAi is ATP dependent yet uncoupled from mRNA translation. During the RNAi reaction, both strands of the …

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