VENTRAL ROOT RESPONSES OF THE HEMISECTED AMPHIBIAN SPINAL CORD TO PERFUSED AMINO ACIDS IN THE PRESENCE OF PROCAINE
作者： R.H. EVANS , J.C. WATKINS
DOI: 10.1111/J.1476-5381.1975.TB07427.X
关键词:
摘要: The use of the procaine-blocked hemisected spinal cord preparation to identify primary action amino acids and their antagonists on amphibian mononeurones is described. 2 Apart from an anomalous effect glycine, responses frog motoneurones were shown be similar those mammalian neurones. 3 In presence procaine, gamma-aminobutyrate (GABA), taurine beta-alanine caused a hyperpolarizing response, measured in ventral roots, whereas L-glutamate and, lesser extent, glycine depolarization. 4 Picrotoxin bicuculline specifically blocked root GABA; strychnine but not L-glutamate, or GABA.
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