Helicobacter pylori and gastric diseases

摘要: The isolation of Helicobacter pylori from clinical specimens by Marshall and Warren 15 years ago1 launched revolutions in gastroenterology microbiology. 2 3 Like other history, the original directions H story have changed response to conflicting ideologies, observation, practices. Currently, enthusiasts, drug companies, lay press are putting pressure on physicians eliminate all patients, symptomatic or not, whom it is detected. There little evidence that this appropriate, management will continue change as new knowledge emerges socioeconomic environments ways relevant medicine. This article looks at past current trends anticipate future these common bacteria disorders associated with them. H one a large family related well adapted persist stomachs vertebrates for life span their hosts. It likely has colonised our since before we became humans.4 Studies primates human populations developing countries suggest that, until last century, nearly humans carried closely stomachs. can thus be regarded indigenous “normal” flora, which most acquire within first few childhood then carry life. With development, fewer children acquiring .5 worldwide phenomenon seems preceded introduction antibiotics, although may been accelerated widespread use. reasons decline prevalence colonisation unknown. Improved nutrition clean water proposed. An alternative hypothesis transmission child …