Bergenin Activates SIRT1 as a Novel Therapeutic Agent for Osteogenesis of Bone Mesenchymal Stem Cells.

作者: Weiduo Hou , Chenyi Ye , Mo Chen , Weixu Li , Xiang Gao

DOI: 10.3389/FPHAR.2019.00618

关键词:

摘要: … enhanced bone formation in a bone defect model and upregulated the expression of SIRT1. … First, although our results indicated that Bergenin upregulated SIRT1 to enhance BMSC …

参考文章(38)
Yosuke Shinozaki, Masako Toda, Jun Ohno, Minoru Kawaguchi, Hirofumi Kido, Tadao Fukushima, Evaluation of bone formation guided by DNA/protamine complex with FGF-2 in an adult rat calvarial defect model. Journal of Biomedical Materials Research Part B. ,vol. 102, pp. 1669- 1676 ,(2014) , 10.1002/JBM.B.33143
Wenjuan Zhou, Zhonghao Liu, Jie Yao, Fei Chi, Kai Dong, Xilong Yue, Teng Teng, Xiaohui Rausch, The Effects of Exenatide Microsphere on Serum BGP and ALP Levels in ZDF Rats after Implantation. Clinical Implant Dentistry and Related Research. ,vol. 17, pp. 765- 770 ,(2015) , 10.1111/CID.12184
Jaesuk Yun, Yeonju Lee, Kyunghwa Yun, Seikwan Oh, Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice Archives of Pharmacal Research. ,vol. 38, pp. 1248- 1254 ,(2015) , 10.1007/S12272-014-0534-Y
Yan Li, Xu He, Yulin Li, Jiaxue He, Björn Anderstam, Göran Andersson, Urban Lindgren, Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals. Journal of Bone and Mineral Research. ,vol. 26, pp. 2656- 2664 ,(2011) , 10.1002/JBMR.480
Nighat Nazir Nighat Nazir, Surrinder Koul Surrinder Koul, MA Qurishi, SC Taneja, SF Ahmad, Sarang Bani Sarang Bani, GN Qazi, Immunomodulatory effect of bergenin and norbergenin against adjuvant-induced arthritis--a flow cytometric study. Journal of Ethnopharmacology. ,vol. 112, pp. 401- 405 ,(2007) , 10.1016/J.JEP.2007.02.023
Tara L. Aghaloo, Christopher M. Amantea, Catherine M. Cowan, Jennifer A. Richardson, Ben M. Wu, Farhad Parhami, Sotirios Tetradis, Oxysterols enhance osteoblast differentiation in vitro and bone healing in vivo Journal of Orthopaedic Research. ,vol. 25, pp. 1488- 1497 ,(2007) , 10.1002/JOR.20437
Huiqiang Chen, Xianbao Liu, Han Chen, Jiang Cao, Ling Zhang, Xinyang Hu, Jiańan Wang, Role of SIRT1 and AMPK in mesenchymal stem cells differentiation. Ageing Research Reviews. ,vol. 13, pp. 55- 64 ,(2014) , 10.1016/J.ARR.2013.12.002
Pei-Chi Tseng, Sheng-Mou Hou, Ruey-Jien Chen, Hsiao-Wen Peng, Chi-Fen Hsieh, Min-Liang Kuo, Men-Luh Yen, Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis. Journal of Bone and Mineral Research. ,vol. 26, pp. 2552- 2563 ,(2011) , 10.1002/JBMR.460
Einav Cohen-Kfir, Hanna Artsi, Avi Levin, Eva Abramowitz, Alon Bajayo, Irina Gurt, Lei Zhong, Agustina D'Urso, Debra Toiber, Raul Mostoslavsky, Rivka Dresner-Pollak, Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor Endocrinology. ,vol. 152, pp. 4514- 4524 ,(2011) , 10.1210/EN.2011-1128