Elevated tumour markers prior to complete tumour removal in patients with pseudomyxoma peritonei predict early recurrence.
作者： F Alexander‐Sefre , K Chandrakumaran , S Banerjee , R Sexton , JM Thomas
DOI: 10.1111/J.1463-1318.2005.00773.X
关键词:
摘要: Objective To assess the potential value of pre-operative CEA, CA 125 and 19–9 in identifying Pseudomyxoma peritonei (PMP) patients at risk recurrence following complete cytoreductive surgery intraperitoneal chemotherapy. Method Between March 1996 October 2001, 35 patients, with documented tumour marker measurements, underwent cytoreduction. Outcome 32 survivors was recorded. Results Median age 53 years (range: 32–74). There were 17[53%] females. In 9/32[28%] all markers normal. The most common abnormality elevated CEA level 14/32[44%]. follow up 23 months 11–74). Recurrence detected 8/32[25%]. 2-year free interval 53% those compared 94% normal CEA. disease intervals 100% 9 preop 66% for group least one abnormal marker. Conclusion PMP or more than serum maker, are developing recurrent disease.
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