作者: Empar Rollano-Hijarrubia , Wiro Niessen , Harrie Weinans , Aad van der Lugt , Rik Stokking
DOI: 10.1097/01.RLI.0000248894.94242.96
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摘要: Objectives: Computed tomography (CT) imaging of small high-density structures, eg, calcifications, is hampered by image blur. This study aims to deconvolve calcifications in the transverse and longitudinal directions while avoiding noise amplification edge-ringing artifacts surrounding low-density structures. Materials Methods: A method referred as histogram-based selective deblurring (HiSD) has been developed generate a restored combining low-intensity (ie, Hounsfield Units) information original with high-intensity deconvolved image. HiSD evaluated on phantom vitro atherosclerotic plaque CT images comparing their corresponding reference micro-CT both qualitatively quantitatively. Results: reduces calcification blur without introducing ringing-artifacts tissues. Calcification area volume measurements are significantly improved (reducing average overestimation 32% 83%, respectively). Conclusions: improves visualization quantification structures imaged vitro.