RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)
作者： Leonid Beigelman , James McSwiggen
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摘要: The present invention relates to compounds, compositions, and methods useful for modulating the expression of genes associated with respiratory pulmonary disease, such as cholinergic muscarinic receptor genes, using short interfering nucleic acid (siNA) molecules. This also activity or other involved in pathways gene and/or by RNA interference (RNAi) small In particular, instant features molecules, (siNA), (siRNA), double-stranded (dsRNA), micro-RNA (miRNA), hairpin (shRNA) molecules used modulate M3 acetylcholine 3 (CHRM3).
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