Decreased survival in diabetic patients with heart failure due to systolic dysfunction

摘要: Background: Prognosis of patients with heart failure (HF) has improved in recent years due to advances therapy. Whether this is also true for diabetic subjects HF clinical practice not been studied a prospective manner. Methods: All and left ventricular systolic dysfunction attending the outpatient clinic at our Veteran's Hospital between October 1999 November 2000 were enrolled study followed prospectively. Electronic medical records accessed data on comorbid conditions, medications, echocardiogram results mortality information. Mean follow-up was 2.7 years. Results: Of 495 study, 293 (59%) had diabetes. Prevalence hypertension, diuretic use angiotensin converting enzyme inhibitor higher among diabetics. Beta-blocker usage equal high both groups (60%). On follow-up, 109/273 (37%) group died, compared 49/202 (24%) non-diabetic group. Independent predictors death diabetes (p<0.005, OR=1.73), age enrollment (p<0.0001, OR=1.06), serum creatinine (p<0.01, OR=1.44) (p=0.038, OR=1.85). associated decreased risk univariate analysis only. Conclusions: Our show that continue have than despite