Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's disease

作者: Lusine Danielyan , Sandra Beer-Hammer , Alexandra Stolzing , Richard Schäfer , Georg Siegel

DOI: 10.3727/096368914X684970

关键词:

摘要: In view of the rapid preclinical development cell-based therapies for neurodegenerative disorders, traumatic brain injury, and tumors, safe efficient delivery targeting therapeuti...

参考文章(81)
Blesch A, Tuszynski M, Ex vivo gene therapy for Alzheimer's disease and spinal cord injury Clinical neuroscience (New York, N.Y.). ,vol. 3, pp. 268- 274 ,(1995)
Praveen Rao, Benjamin M. Segal, Experimental autoimmune encephalomyelitis Methods in molecular medicine. ,vol. 102, pp. 363- 375 ,(2004) , 10.1385/1-59259-805-6:363
Marina Saresella, Ivana Marventano, Elena Calabrese, Federica Piancone, Veronica Rainone, Andrea Gatti, Margherita Alberoni, Raffaello Nemni, Mario Clerici, A Complex Proinflammatory Role for Peripheral Monocytes in Alzheimer's Disease Journal of Alzheimer's Disease. ,vol. 38, pp. 403- 413 ,(2013) , 10.3233/JAD-131160
Frédérique Bard, Catherine Cannon, Robin Barbour, Rae-Lyn Burke, Dora Games, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Johnson-Wood, Karen Khan, Dora Kholodenko, Mike Lee, Ivan Lieberburg, Ruth Motter, Minh Nguyen, Ferdie Soriano, Nicki Vasquez, Kim Weiss, Brent Welch, Peter Seubert, Dale Schenk, Ted Yednock, Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nature Medicine. ,vol. 6, pp. 916- 919 ,(2000) , 10.1038/78682
Soon-Tae Lee, Kon Chu, Jung-Eun Park, Keun-Hwa Jung, Daejong Jeon, Ji-Youn Lim, Sang Kun Lee, Manho Kim, Jae-Kyu Roh, Erythropoietin improves memory function with reducing endothelial dysfunction and amyloid-beta burden in Alzheimer's disease models. Journal of Neurochemistry. ,vol. 120, pp. 115- 124 ,(2012) , 10.1111/J.1471-4159.2011.07534.X
Terrence Town, Yasmina Laouar, Christopher Pittenger, Takashi Mori, Christine A Szekely, Jun Tan, Ronald S Duman, Richard A Flavell, Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology Nature Medicine. ,vol. 14, pp. 681- 687 ,(2008) , 10.1038/NM1781
Selene Lomoio, Irene López-González, Ester Aso, Margarita Carmona, Benjamín Torrejón-Escribano, Elda Scherini, Isidro Ferrer, Cerebellar amyloid-β plaques: disturbed cortical circuitry in AβPP/PS1 transgenic mice as a model of familial Alzheimer's disease. Journal of Alzheimer's Disease. ,vol. 31, pp. 285- 300 ,(2012) , 10.3233/JAD-2012-112198
Michael I. Assaraf, Zuanel Diaz, Adrienne Liberman, Wilson H. Miller, Zoe Arvanitakis, Yan Li, David A. Bennett, Hyman M. Schipper, Brain Erythropoietin Receptor Expression in Alzheimer Disease and Mild Cognitive Impairment Journal of Neuropathology and Experimental Neurology. ,vol. 66, pp. 389- 398 ,(2007) , 10.1097/NEN.0B013E3180517B28
J. Koenigsknecht-Talboo, M. Meyer-Luehmann, M. Parsadanian, M. Garcia-Alloza, M. B. Finn, B. T. Hyman, B. J. Bacskai, D. M. Holtzman, Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-Aβ Antibody Administration in PDAPP Mice The Journal of Neuroscience. ,vol. 28, pp. 14156- 14164 ,(2008) , 10.1523/JNEUROSCI.4147-08.2008