Current Status of Hepatitis E Virus Infection in Korea

作者: Sook-Hyang Jeong

DOI: 10.5009/GNL.2011.5.4.427

关键词:

摘要: Hepatitis E virus (HEV) is an emerging pathogen associated with acute viral hepatitis, and HEV becoming increasingly recognized. Approximately 2% of hepatitis caused by HEV, 18 cases have been reported in Korea. Of these cases, only two involved a history travel from India, which suggests that they were imported cases. The remaining include sporadic case genotype 4 isolates identification the full genome sequence, as well another developed after ingestion raw bile juice wild bear living on mountain southern Moreover, 3 shows close genetic homology swine Korea, has detected collected human serum samples. Therefore, genotypes are currently circulating Korean community may be related to zoonotic transmission food-borne infection. anti-HEV seroprevalence 17% 27% population infection autochthonously circulating, thereby resulting subclinical Given discrepancies among assays, diagnosis should made caution using adequate antibody RNA preferably stool. Further virological characterization epidemiological study warranted.

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