Proliferative and differentiation potential of individual clones derived from bone marrow stromal precursor cells

作者: R. K. Chailakhyan , Yu. V. Gerasimov , A. I. Kuralesova , N. V. Latsinik , E. N. Genkina

DOI: 10.1023/A:1012316218732

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摘要: We present the results of a study on proliferative and differentiation potential individual clones stromal fibroblasts growing in monolayer cultures bone marrow cells. Each precursor cell yielding large colony primary culture is capable up to 34 doublings vitro. The transplantation or monoclonal strains into open system formation microenvironment consisting reticular tissue suitable for all three lines hemopoiesis. Evidence has been obtained that, closed system, are bone, cartilaginous, tissues. In other words, adult organism common these

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