ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer.
作者： A Latina , G Viticchiè , A M Lena , M C Piro , M Annicchiarico-Petruzzelli
DOI: 10.1038/ONC.2015.222
关键词:
摘要: … Furthermore, upon p63 downregulation, we observed increased expression of antistress response genes such as catalase, which is important for protecting cells from oxidative damage …
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G. Browne, R. Cipollone, A. M. Lena, V. Serra, H. Zhou, H. van Bokhoven, V. Dotsch, D. Merico, R. Mantovani, A. Terrinoni, R. A. Knight, E. Candi, G. Melino, Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias Journal of Cell Science. ,vol. 124, pp. 2200- 2207 ,(2011) , 10.1242/JCS.079327
E Candi, A Rufini, A Terrinoni, D Dinsdale, M Ranalli, A Paradisi, V De Laurenzi, L G Spagnoli, M V Catani, S Ramadan, R A Knight, G Melino, Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice Cell Death & Differentiation. ,vol. 13, pp. 1037- 1047 ,(2006) , 10.1038/SJ.CDD.4401926
R J Shaw, M M Omar, S Rokadiya, F A Kogera, D Lowe, G L Hall, J A Woolgar, J Homer, T Liloglou, J K Field, J M Risk, Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer British Journal of Cancer. ,vol. 101, pp. 139- 144 ,(2009) , 10.1038/SJ.BJC.6605121
A. Rufini, M. V. Niklison-Chirou, S. Inoue, R. Tomasini, I. S. Harris, A. Marino, M. Federici, D. Dinsdale, R. A. Knight, G. Melino, T. W. Mak, TAp73 depletion accelerates aging through metabolic dysregulation Genes & Development. ,vol. 26, pp. 2009- 2014 ,(2012) , 10.1101/GAD.197640.112
Matthias Sommer, Nina Poliak, Sunil Upadhyay, Edward A. Ratovitski, Barry D. Nelkin, Lawrence A. Donehower, David Sidransky, ΔNp63&alpha Overexpression Induces Downregulation of Sirt1 and an Accelerated Aging Phenotype in the Mouse Cell Cycle. ,vol. 5, pp. 2005- 2011 ,(2006) , 10.4161/CC.5.17.3194
A. B. Truong, M. Kretz, T. W. Ridky, R. Kimmel, P. A. Khavari, p63 regulates proliferation and differentiation of developmentally mature keratinocytes Genes & Development. ,vol. 20, pp. 3185- 3197 ,(2006) , 10.1101/GAD.1463206
Alexandra S. Bause, Mary S. Matsui, Marcia C. Haigis, The protein deacetylase SIRT3 prevents oxidative stress-induced keratinocyte differentiation. Journal of Biological Chemistry. ,vol. 288, pp. 36484- 36491 ,(2013) , 10.1074/JBC.M113.472324
Alessandro Rufini, Miguel Weil, Frank McKeon, Alberto Barlattani, Gerry Melino, Eleonora Candi, p63 protein is essential for the embryonic development of vibrissae and teeth Biochemical and Biophysical Research Communications. ,vol. 340, pp. 737- 741 ,(2006) , 10.1016/J.BBRC.2005.12.065
A Patel, D G A Burton, K Halvorsen, W Balkan, T Reiner, C Perez-Stable, A Cohen, A Munoz, M G Giribaldi, S Singh, D J Robbins, D M Nguyen, P Rai, MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. ,vol. 34, pp. 2586- 2596 ,(2015) , 10.1038/ONC.2014.195
C Wiel, A Augert, D F Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, H Lallet-Daher, C Reynaud, I Treilleux, L Bartholin, E Lelievre, D Bernard, Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis Cell Death and Disease. ,vol. 4, ,(2013) , 10.1038/CDDIS.2013.382