Critical appraisal of treatment techniques based on conventional photon beams, intensity modulated photon beams and proton beams for therapy of intact breast.

摘要: Purpose: To analyse different treatment techniques with conventional photon beams, intensity modulated and proton beams for intact breast irradiation patients in whom would cause potentially dangerous lung irradiation. Material methods: Five cancer highly concave tissue volume around the were considered at planning level order to assess suitability of techniques. Three-dimensional dose distributions two-field tangential treatment, radiotherapy (IMRT), three-field non-IMRT, IMRT, single-field investigated, aiming assessing possibility reduce below risk levels. Analysis dose‐volume histograms related physical biological parameters (significant minimum, maximum mean doses, conformity indexes equivalent uniform (EUD)) planned target (PTV) was carried out. Dose plans compared technique. Results: PTV coverage comparable non-IMRT IMRT (EUD from 47.1 49.4 Gy), improved ¼ 49:8 Gy). Lung reduced, terms dose, (9.5 Gy) technique (3.5 respect (12.9 Gy); also a reduction irradiated high doses observed. Better results could be achieved protons. In addition, cardiac reduced those Conclusions: Geometrically difficult thus reducing which is proposed as standard this category patients. Intensity only marginally more successful than corresponding treatments, while protons offer excellent results. q 2002 Elsevier Science Ireland Ltd. All rights reserved.