CCAT2: A novel oncogenic long non-coding RNA in human cancers.
作者： Yu Xin , Zheng Li , Heyi Zheng , Matthew T.V. Chan , William Ka Kei Wu
DOI: 10.1111/CPR.12342
关键词:
摘要: Colon cancer-associated transcript 2 (CCAT2) was originally identified as an oncogenic long non-coding RNA in colorectal cancer. Since its discovery, the role of CCAT2 has been increasingly demonstrated human cancers. In this connection, upregulation is frequently reported and very often associated with tumour progression poor clinical outcomes. Functionally, knockdown could induce cancer cell apoptosis suppress proliferation invasiveness, suggesting that might be a therapeutic target. The present review summarized current literature concerning expression functional malignancies.
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