Oseltamivir-resistant 2009–2010 pandemic influenza A (H1N1) in an immunocompromised patient
作者： P.A Chan , N.T Connell , A.M Gabonay , B. Westley , J.M Larkin
DOI: 10.1111/J.1469-0691.2010.03212.X
关键词:
摘要: Although neuraminidase inhibitors are active against most 2009-2010 pandemic influenza A (H1N1) swine-origin strains, sporadic cases of oseltamivir resistance have been described. Since April 2009, 54 oseltamivir-resistant H1N1 reported in the USA (http://www.cdc.gov/flu/weekly/; accessed 1 February 2010). Approximately 1.4% tested isolates resistant. We report a patient with an underlying hematological malignancy who was hospitalized and whose strain developed during therapy.
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