Adrenergic mechanisms in the control of corticotrophin secretion.

摘要: Although the data on effects of adrenergic mechanisms secretion ACTH had seemed confusing, most discrepancies are probably explicable basis methodological differences. In present state knowledge, following conclusions seem reasonable. (1) both man and rat, activation central alpha-1 adrenoceptors is followed by increased this mechanism important in control hormone under some physiological circumstances. (2) man, peripheral circulating catecholamines do not stimulate conditions. This conclusion also applies to anterior pituitary corticotrophs rat. (3) beta-2 adrenoceptor agonists intermediate lobe a direct action that physiologically relevant. (4) The role beta alpha-2 requires further investigation.