Higher platelet distribution width predicts poor prognosis in laryngeal cancer

摘要: // Huan Zhang 1, * , Li Liu 2, Shuang Fu Yan-Song 3 Changsong Wang Tiemin 4 Zhi-Ping 5 Rui-Tao 6 and Kai-Jiang Yu 3, 1 Department of Internal Medicine, Harbin Medical University Cancer Hospital, University, Harbin, Heilongjiang, 150081, China 2 Histology Embryology, Intensive Care Unit, Division Hypothalamic Research, Texas Southwestern Center, Dallas, TX, 75390, USA Departments Medicine Molecular Biology, Heilongjiang Academy Science, These authors have contributed equally to this work Correspondence to: Wang, email: ruitaowang@126.com Yu, kaijiang_yu@yeah.net Keywords: laryngeal cancer, platelet distribution width, prognosis, survival Received: March 29, 2017      Accepted: May 01, Published: 30, 2017 ABSTRACT Background: Activated platelets promote cancer progression metastasis. However, the prognostic value indices in remains poorly understood. The purpose study was investigate predictive significance cancer. Results: Of 241 patients, high width (PDW) levels were observed 116 (48.1 %) patients. In Kaplan-Meier analysis, increased PDW significantly associated with a poorer overall (p < 0.001). multivariate Cox model, an independent index for (HR=4.381, 95% CI=2.313-8.298, P Method: retrospective included consecutive patients between January 2009 December 2009. relationships clinicopathological characteristics analyzed. method regression used evaluate impact PDW. Conclusions: Elevated might be novel marker