Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow–derived mesenchymal stromal cells

作者: Armel Hervé Nwabo Kamdje , Federico Mosna , Francesco Bifari , Veronica Lisi , Giulio Bassi

DOI: 10.1182/BLOOD-2010-12-326694

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摘要: … By contrast, active Caspase-3 down-regulation and Bcl-2 overexpression were reverted by adding either anti-Notch-3 + anti–Notch-4 Abs or GSI XII in presence of hydrocortisone (…

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