KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

作者: Maria Debiec-Rychter , Raf Sciot , Axel Le Cesne , Marcus Schlemmer , Peter Hohenberger

DOI: 10.1016/J.EJCA.2006.01.030

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摘要: … The clinical activity of imatinib has been confirmed in GISTs, both in an … which the highest feasible dose of imatinib was defined as 400 mg twice a day, and in phase II studies with doses …

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