Amperimetric Biosensor Based on Carbon Nanotube and Plasma Polymer

摘要: Carbon nanotubes (CNTs) have been the focus of considerable studies since their discovery by Iijima (Iijima, 1991). CNTs are considered to be formed folding graphene layers into carbon cylinders. They two distinct structural types: single-walled (SWCNTs) and multi-walled (MWCNTs). A SWCNT is a single shell extending from end with 1.3-2 nm tube diameter. MWCNT composed several coaxial shells, each rolled graphite sheets, diameters varying 2 50 distance between sheets being about 0.34 nm. many new applications electronic devices, such as field-effect transistors (Maki et al., 2006; Ohnaka 2006) gas sensors (Ueda Wongwiriyapan 2005), because unique properties, geometric structure, high mechanical strength, chemical stability. Recently, amperometric biosensors using increasingly reported. The typical structure CNT-based biosensor combination biomacromolecules (e.g., enzymes) in vicinity electrode. Because well-defined nanostructure CNTs, good connection enzymes can obtained. also enhance electron transfer reaction center enzyme Therefore, performance characteristics realized. Many strategies has reported: treatment nitric or sulfonic acid order introduce chemically active functional groups (Liu 2005a; Gooding 2003; Azamian 2002; Kim Li 2005; Liu 2006), which enables subsequent modification. Another strategy dispersion binder Nafion (Tang 2004; Tsai Hrapovic Lee 2007), Teflon (Wang & Musameh, 2003), sol-gel (Gavalas Salimi Yang Kandimalla poly(methyl methacrylate) (PMMA) (Rege redox hydrogel (Joshi Wang poly(dimethyldiallylammonium chloride) (Zhao Ju, Yan chitosan 2005b; Rivas electropolymerized film (Tsai Pan 2005). However, these methods require that other biomolecules receive careful retain tertiary structure. Moreover, when wet processes, it difficult control nanoscale fabrication. method where directly treated plasma recently reported (Khare Khare Plank