Postprandial Dysmetabolism and Oxidative Stress in Type 2 Diabetes: Pathogenetic Mechanisms and Therapeutic Strategies.
作者： Barbara Sottero , Simona Gargiulo , Isabella Russo , Cristina Barale , Giuseppe Poli
DOI: 10.1002/MED.21349
关键词:
摘要: Postprandial dysmetabolism in type 2 diabetes (T2D) is known to impact the progression and evolution of this complex disease process. However, underlying pathogenetic mechanisms still require full elucidation provide guidance for prevention treatment. This review focuses on marked redox changes inflammatory stimuli provoked by spike blood glucose lipids T2D individuals after meals. All causes exacerbated postprandial oxidative stress were analyzed, also considering consequence enhanced inflammation vascular damage. Based in-depth analysis, current strategies pharmacologic management critically reexamined with particular emphasis their potential redox-related rationale.
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