Potential Application of Adult Stem Cells in Retinal Repair—Challenge for Regenerative Medicine

作者: Anna Machalińska , Bartłomiej Baumert , Leszek Kuprjanowicz , Barbara Wiszniewska , Danuta Karczewicz

DOI: 10.1080/02713680903050592

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摘要: Stem cells (SCs) maintain the balance among somatic cell populations in various tissues and are responsiblefororganregeneration.Theremarkableprogressofregenerativemedicineinthelastfew years indicates promise for use of SCs ophthalmic disorder treatment. This review describes current view on hierarchy SC compartment presents latest attempts to adult regeneration retina. Research performed primarily animal models gives hope using similar strategies humans. However, search optimal source therapy continues. We briefly discuss potential sources that could be employed regenerative medicine, particularly focusing recently identified, very small embryonic-like (VSEL-SCs). These even present bone marrow older patients harvested from cord blood. believe VSEL-SCs, after establishment ex vivo expansion differentiation protocols, harnessed retina regeneration.

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