Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
作者： Helena Linardou , Issa J Dahabreh , Dimitra Kanaloupiti , Fotios Siannis , Dimitrios Bafaloukos
DOI: 10.1016/S1470-2045(08)70206-7
关键词:
摘要: … The findings of this systematic review strongly suggest that somatic mutations leading to gain-of-function and constitutive signalling of the k-RAS pathway(s) represent a strong …
elsevier.com
sci-hub.se 参考文章(94)
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework* Clinical Pharmacology & Therapeutics. ,vol. 69, pp. 89- 95 ,(2001) , 10.1067/MCP.2001.113989
Roy S. Herbst, Masahiro Fukuoka, José Baselga, Gefitinib — a novel targeted approach to treating cancer Nature Reviews Cancer. ,vol. 4, pp. 956- 965 ,(2004) , 10.1038/NRC1506
C. Bokemeyer, I. Bondarenko, J. T. Hartmann, F. G. De Braud, C. Volovat, J. Nippgen, C. Stroh, I. Celik, P. Koralewski, KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: The OPUS experience Journal of Clinical Oncology. ,vol. 26, pp. 4000- 4000 ,(2008) , 10.1200/JCO.2008.26.15_SUPPL.4000
John Wen-Cheng Chang, Hui-Ping Liu, Meng-Heng Hsieh, Yueh-Fu Fang, Meng-Shu Hsieh, Jia-Juan Hsieh, Yu-Ting Chiu, Hsien-Yu Tsai, Yi-Hsuan Chen, Ya-Ting Chen, Hui-Yu Hsu, Ying-Tsong Chen, Shih-Feng Tsai, Yi-Rong Chen, Bae-Li Hsi, Shiu-Feng Huang, Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients Lung Cancer. ,vol. 61, pp. 328- 339 ,(2008) , 10.1016/J.LUNGCAN.2008.01.009
Nancy E. Hynes, Heidi A. Lane, ERBB receptors and cancer: the complexity of targeted inhibitors. Nature Reviews Cancer. ,vol. 5, pp. 341- 354 ,(2005) , 10.1038/NRC1609
William Pao, Vincent A. Miller, Epidermal Growth Factor Receptor Mutations, Small-Molecule Kinase Inhibitors, and Non–Small-Cell Lung Cancer: Current Knowledge and Future Directions Journal of Clinical Oncology. ,vol. 23, pp. 2556- 2568 ,(2005) , 10.1200/JCO.2005.07.799
Takayuki Kosaka, Yasushi Yatabe, Hideki Endoh, Kimihide Yoshida, Toyoaki Hida, Masahiro Tsuboi, Hirohito Tada, Hiroyuki Kuwano, Tetsuya Mitsudomi, Analysis of Epidermal Growth Factor Receptor Gene Mutation in Patients with Non–Small Cell Lung Cancer and Acquired Resistance to Gefitinib Clinical Cancer Research. ,vol. 12, pp. 5764- 5769 ,(2006) , 10.1158/1078-0432.CCR-06-0714
Donna F Stroup, Jesse A Berlin, Sally C Morton, Ingram Olkin, G David Williamson, Drummond Rennie, David Moher, Betsy J Becker, Theresa Ann Sipe, Stephen B Thacker, Meta-analysis of Observational Studies in EpidemiologyA Proposal for Reporting JAMA. ,vol. 283, pp. 2008- 2012 ,(2000) , 10.1001/JAMA.283.15.2008
Olivier Dassonville, Alexandre Bozec, Jean Louis Fischel, Gerard Milano, EGFR targeting therapies: monoclonal antibodies versus tyrosine kinase inhibitors. Similarities and differences. Critical Reviews in Oncology Hematology. ,vol. 62, pp. 53- 61 ,(2007) , 10.1016/J.CRITREVONC.2006.12.008
Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature. ,vol. 418, pp. 934- 934 ,(2002) , 10.1038/418934A