Molecular mechanisms and treatment strategies for Dupuytren's disease.

摘要: Dupuytren’s disease (DD) is a common of the hand and characterized by thickening palmar fascia formation tight collagenous cords. At present, incurable molecular pathophysiology DD unknown. Surgery remains most commonly used treatment for DD, but this requires extensive postoperative therapy associated with high rates recurrence. Over past decades, more indepth exploration basis has raised hopes developing new modalities. This paper reviews clinical presentation disease, as well current emerging treatment. It also explores implications findings in laboratory future