β-catenin - A linchpin in colorectal carcinogenesis?

作者: Newton Alexander Chiang Shuek Wong , Massimo Pignatelli

DOI: 10.1016/S0002-9440(10)64856-0

关键词:

摘要: … , are now known to exist in truncated forms that repress β-catenin/TCF transcriptional activity.… tyrosine phosphorylation of β-catenin and, hence, disruption of the adherens complex.23, …

参考文章(139)
P. S. Bhathal, G. P. Young, T. Erler, R. J. James, H. C. Ee, Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma. American Journal of Pathology. ,vol. 147, pp. 586- 592 ,(1995)
Jürgen Behrens, Walter Birchmeier, Cell-cell adhesion in invasion and metastasis of carcinomas. Cancer treatment and research. ,vol. 71, pp. 251- 266 ,(1994) , 10.1007/978-1-4615-2592-9_13
Maureen J. O’Sullivan, Tommie V. Mccarthy, Cuimin T. Doyle, Familial Adenomatous Polyposis: From Bedside to Benchside American Journal of Clinical Pathology. ,vol. 109, pp. 521- 526 ,(1998) , 10.1093/AJCP/109.5.521
Shoji Nakamori, David M. Ota, Karen R. Cleary, Keiro Shirotani, Tatsuro Irimura, MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma Gastroenterology. ,vol. 106, pp. 353- 361 ,(1994) , 10.1016/0016-5085(94)90592-4
Stephen Edward Hiscox, Wen Guo Jiang, Hepatocyte growth factor/scatter factor disrupts epithelial tumour cell-cell adhesion: involvement of beta-catenin. Anticancer Research. ,vol. 19, pp. 509- 517 ,(1999)
Ana L. Giannini, Maria d. M. Vivanco, Robert M. Kypta, α-Catenin Inhibits β-Catenin Signaling by Preventing Formation of a β-Catenin·T-cell Factor·DNA Complex Journal of Biological Chemistry. ,vol. 275, pp. 21883- 21888 ,(2000) , 10.1074/JBC.M001929200
Varki N, Bissonnette M, Wali Rk, Boss Gr, Khare S, Nguyen L, Hart J, Skarosi S, Brasitus Ta, Zhang Y, von Lintig Fc, Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1. Cancer Research. ,vol. 60, pp. 4602- 4609 ,(2000)
Barry Iacopetta, Jacqueline Gayet, Xiao-Ping Zhou, Gilles Thomas, Richard Hamelin, Alex Duval, Frequent Frameshift Mutations of the TCF-4 Gene in Colorectal Cancers with Microsatellite Instability Cancer Research. ,vol. 59, pp. 4213- 4215 ,(1999)
Wouter W. Van Solinge, Finn C. Nielsen, Lennart Friis-Hansen, Ursula G. Falkmer, Jens F. Rehfeld, Expression but incomplete maturation of progastrin in colorectal carcinomas Gastroenterology. ,vol. 104, pp. 1099- 1107 ,(1993) , 10.1016/0016-5085(93)90279-L