Initial Presentation With Stage IV Colorectal Cancer

作者: Seth A. Rosen

DOI: 10.1001/ARCHSURG.135.5.530

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摘要: Hypothesis The appropriate surgical treatment of patients with colorectal cancer who are found on initial presentation to have stage IV disease is controversial. With presumed limited life expectancy, the role primary colon or rectal resection has been questioned, as utility synchronous hepatic resection. Design A retrospective chart review. Setting University Chicago Hospitals, Chicago, Ill, a tertiary-care referral center. Patients One hundred twenty were identified through Hospitals Tumor Registry whose showed and underwent laparotomy. Main Outcome Measures end points study perioperative morbidity mortality overall survival. Results Median survival 5-year 14.4 months 10%, respectively. Survival was greater for younger than 65 years those aged older (18.3 vs 9.8 months; P =.007). Carcinomatosis associated significantly decreased when compared less extensive (6.7 18.1 Conclusions Age older, carcinomatosis, (bilobar) liver involvement increased postoperative may negate any potential benefit derive from lesion. substantial number metastases protracted that justifies tumor at presentation. Despite presence disease, and, feasible, indicated.

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