Lymphocyte Function in IgA Nephropathy

摘要: IgA nephropathy is now an accepted disease entity that characterized by preponderant mesangial deposition of [1, 2]. An increasing body evidence suggests the deposits are likely to be either polymers or IgA-dominant immune complexes [3, 4]. These seem circulate in blood because a frequent recurrence this after renal allotransplantation [5, 6] and rapid disappearance grafted kidney from donor with unsuspected [7]. The presence such circulation increased synthesis patients nephropathy. Although mechanism regulation has not been fully elucidated, rapidly accumulating indicates interaction B T cells plays key role IgA, isotype known highly T-cell specific [8]. discussion on altered lymphocyte function chapter limited primary observed various other diseases as alcoholic cirrhosis [9].