A reproducible brain tumour model established from human glioblastoma biopsies
作者： Jian Wang , Hrvoje Miletic , Per Ø Sakariassen , Peter C Huszthy , Hege Jacobsen
关键词:
摘要: Background Establishing clinically relevant animal models of glioblastoma multiforme (GBM) remains a challenge, and many commonly used cell line-based do not recapitulate the invasive growth patterns patient GBMs. Previously, we have reported formation highly tumour xenografts in nude rats from human However, implementing based on primary tissue requires that these can be sufficiently standardised with consistently high take rates.
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