Unusual usage of wobble modifications in mitochondrial tRNAs of the nematodeAscaris suum

作者: Masayuki Sakurai , Takashi Ohtsuki , Tsutomu Suzuki , Kimitsuna Watanabe

DOI: 10.1016/J.FEBSLET.2005.04.009

关键词:

摘要: Abstract To understand the decoding property of nematode mitochondrial tRNAs with unusual secondary structures, post-transcriptional modifications at wobble positions Ascaris suum corresponding to two-codon families ending a purine were analyzed. 5-Carboxymethylaminomethyluridine (cmnm 5 U) was identified tRNA Lys , Glu and Gln while 5-carboxymethylaminomethyl-2-thiouridine s 2 present in UAA Leu Trp . In most bacterial tRNAs, 2-thiouridine derivative is for Lys, Gln. These no report that cmnm U used The usage might assist mRNAs.

参考文章(36)
Yoshiyuki Kuchino, Naohiro Hanyu, Susumu Nishimura, Analysis of modified nucleosides and nucleotide sequence of tRNA. Methods in Enzymology. ,vol. 155, pp. 379- 396 ,(1987) , 10.1016/0076-6879(87)55026-1
Shigeyuki Yokoyama, Susumu Nishimura, Modified Nucleosides and Codon Recognition American Society of Microbiology. pp. 207- 223 ,(1995) , 10.1128/9781555818333.CH12
Hiromichi Tsurui, Rieko Furushima, Kimitsuna Watanabe, Takuya Ueda, Yoh Ichi Watanabe, Kiyoshi Kita, Shinzaburo Takamiya, Kazuya Nishikawa, Primary and higher order structures of nematode (Ascaris suum) mitochondrial tRNAs lacking either the T or D stem. Journal of Biological Chemistry. ,vol. 269, pp. 22902- 22906 ,(1994) , 10.1016/S0021-9258(17)31730-1
Eric Madore, Catherine Florentz, Richard Giegé, Shun-ichi Sekine, Shigeyuki Yokoyama, Jacques Lapointe, Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl-tRNA synthetase. Predominant and distinct roles of the mnm5 and s2 modifications of U34. FEBS Journal. ,vol. 266, pp. 1128- 1135 ,(1999) , 10.1046/J.1432-1327.1999.00965.X
M Yaniv, WR Folk, The nucleotide sequences of the two glutamine transfer ribonucleic acids from Escherichia coli. Journal of Biological Chemistry. ,vol. 250, pp. 3243- 3253 ,(1975) , 10.1016/S0021-9258(19)41506-8
Steven C. Pomerantz, James A. McCloskey, [44] Analysis of RNA hydrolyzates by liquid chromatography-mass spectrometry Mass Spectrometry. ,vol. 193, pp. 796- 824 ,(1990) , 10.1016/0076-6879(90)93452-Q
Hanna Sierzputowska-Gracz, Elzbieta Sochacka, Andrzej Malkiewicz, Kenneth Kuo, Charles W. Gehrke, Paul F. Agris, Chemistry and structure of modified uridines in the anticodon, wobble position of transfer RNA are determined by thiolation Journal of the American Chemical Society. ,vol. 109, pp. 7171- 7177 ,(1987) , 10.1021/JA00257A044
Malene K Krüger, Michael A Sørensen, Aminoacylation of hypomodified tRNAGlu in vivo. Journal of Molecular Biology. ,vol. 284, pp. 609- 620 ,(1998) , 10.1006/JMBI.1998.2197
Min Hu, Neil B. Chilton, Robin B. Gasser, The mitochondrial genomes of the human hookworms, Ancylostoma duodenale and Necator americanus (Nematoda: Secernentea) International Journal for Parasitology. ,vol. 32, pp. 145- 158 ,(2002) , 10.1016/S0020-7519(01)00316-2
Akiko Soma, Yoshiho Ikeuchi, Satoru Kanemasa, Kazuo Kobayashi, Naotake Ogasawara, Tomotake Ote, Jun-ichi Kato, Kimitsuna Watanabe, Yasuhiko Sekine, Tsutomu Suzuki, An RNA-Modifying Enzyme that Governs Both the Codon and Amino Acid Specificities of Isoleucine tRNA Molecular Cell. ,vol. 12, pp. 689- 698 ,(2003) , 10.1016/S1097-2765(03)00346-0