Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

作者: Ceri A. Fielding , Gareth W. Jones , Rachel M. McLoughlin , Louise McLeod , Victoria J. Hammond

DOI: 10.1016/J.IMMUNI.2013.10.022

关键词:

摘要: Fibrosis in response to tissue damage or persistent inflammation is a pathological hallmark of many chronic degenerative diseases. By using a model of acute peritoneal inflammation, …

参考文章(60)
Anne Puel, Capucine Picard, Mathie Lorrot, Charlotte Pons, Maya Chrabieh, Lazaro Lorenzo, Maria Mamani-Matsuda, Emmanuelle Jouanguy, Dominique Gendrel, Jean-Laurent Casanova, None, Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6. Journal of Immunology. ,vol. 180, pp. 647- 654 ,(2008) , 10.4049/JIMMUNOL.180.1.647
Simon D. Oldroyd, Graham L. Thomas, Giulio Gabbiani, A. Meguid El Nahas, Interferon-γ inhibits experimental renal fibrosis Kidney International. ,vol. 56, pp. 2116- 2127 ,(1999) , 10.1046/J.1523-1755.1999.00775.X
G D Sempowski, R P Phipps, M P Beckmann, S Derdak, Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. Journal of Immunology. ,vol. 152, pp. 3606- 3614 ,(1994)
Simon J. Davies, Louise Phillips, Patrick F. Naish, Gavin I. Russell, Peritoneal Glucose Exposure and Changes in Membrane Solute Transport with Time on Peritoneal Dialysis Journal of The American Society of Nephrology. ,vol. 12, pp. 1046- 1051 ,(2001) , 10.1681/ASN.V1251046
Claire J Greenhill, Stefan Rose-John, Rami Lissilaa, Walter Ferlin, Matthias Ernst, Paul J Hertzog, Ashley Mansell, Brendan J Jenkins, None, IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3 Journal of Immunology. ,vol. 186, pp. 1199- 1208 ,(2011) , 10.4049/JIMMUNOL.1002971
Mitsunari Yamamoto, Kazuyuki Yoshizaki, Tadamitsu Kishimoto, Hiroaki Ito, IL-6 Is Required for the Development of Th1 Cell-Mediated Murine Colitis Journal of Immunology. ,vol. 164, pp. 4878- 4882 ,(2000) , 10.4049/JIMMUNOL.164.9.4878
Simon A. Jones, Directing transition from innate to acquired immunity: defining a role for IL-6. Journal of Immunology. ,vol. 175, pp. 3463- 3468 ,(2005) , 10.4049/JIMMUNOL.175.6.3463
Jason S Stumhofer, Jonathan S Silver, Arian Laurence, Paige M Porrett, Tajie H Harris, Laurence A Turka, Matthias Ernst, Christiaan J M Saris, John J O'Shea, Christopher A Hunter, Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 Nature Immunology. ,vol. 8, pp. 1363- 1371 ,(2007) , 10.1038/NI1537