Clinical Application of Flow Cytometry for DNA Analysis of Solid Tumors

作者: Kohsuke Sasaki , Tomoyuki Murakami

DOI: 10.1111/J.1440-1827.1992.TB01105.X

关键词:

摘要: Recent developments of flow cytometry (FCM) technology which make multiple correlative biological measurements on normal and neoplastic cells is affecting areas diagnostic pathology as well research fields, a general understanding FCM techniques essential for pathologists. Today, DNA tumors also becomes routine in the clinical and/or pathological laboratory aid cancer diagnosis treatment. It can contribute to supplemental method conventional histopathology, ploidy percentage S-phase fraction are considered complementary prognostic parameters independent stage disease. This article reviews applications focusing solid tumors, related practical issues, such methodology nuclear measurement, interpretation histograms relationship features human tumors.

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