Characterization of Squamous Cell Bladder Tumors by Flow Cytometric Deoxyribonucleic Acid Analysis: A Report of 100 Cases
作者： Atallah A. Shaaban , Bernhard Tribukait , Abdel-Fattah A. El-Bedeiwy , Mohamed A. Ghoneim
DOI: 10.1016/S0022-5347(17)39614-3
关键词:
摘要: Abstract We studied 100 cases of squamous cell carcinoma the bladder by flow cytometry after cystectomy. Tumors were classified according to deoxyribonucleic acid profile into diploid or aneuploid. Proliferation tumors was assessed from proportions S-phase cells. The cytometric data correlated histopathological stage and grade. Grade 1 could be subdivided aneuploid in 60 40% cases, respectively, while 95% grade 2 all 3 Diploid had low proliferation rates, significantly higher values. A high frequency muscle invasive noted. Tumor heterogeneity comparing material superficial deep tumor areas, which agreement 77% cases. By biopsy with that obtained washings, yielded better information regarding ploidy half tumors. These results indicate offers an additional objective method characterize carcinoma. ( J. Urol., 144: 879–883, 1990 )
elsevier.com
sci-hub.se 参考文章(18)
Bernhard Tribukait, Clinical DNA flow cytometry. Medical oncology and tumor pharmacotherapy. ,vol. 1, pp. 211- 218 ,(1984) , 10.1007/BF02934525
Jerome P. Richie, Robert D. Blute, Jerry Waisman, Immunologic indicators of prognosis in bladder cancer: the importance of cell surface antigens. The Journal of Urology. ,vol. 123, pp. 22- 24 ,(1980) , 10.1016/S0022-5347(17)55757-2
Avery A. Sandberg, Chromosome Markers and Progression in Bladder Cancer Cancer Research. ,vol. 37, pp. 2950- 2956 ,(1977)
R. C. B. Pugh, The pathology of cancer of the bladder.An editorial overview Cancer. ,vol. 32, pp. 1267- 1274 ,(1973) , 10.1002/1097-0142(197311)32:5<1267::AID-CNCR2820320536>3.0.CO;2-6
E.C.M. Ooms, W.A.D. Anderson, C.L. Alons, Mathilde E. Boon, R.W. Veldhuizen, Analysis of the performance of pathologists in the grading of bladder tumors Human Pathology. ,vol. 14, pp. 140- 143 ,(1983) , 10.1016/S0046-8177(83)80242-1
B. Tribukait, Flow cytometry in assessing the clinical aggressiveness of genito-urinary neoplasms World Journal of Urology. ,vol. 5, pp. 108- 122 ,(1987) , 10.1007/BF00327068
G. D. CHISHOLM, J. R. HINDMARSH, A. G. HOWATSON, J. N. WEBB, A. BUSUTTIL, T. B. HARGREAVE, J. E. NEWSAM, TNM (1978) in bladder cancer: use and abuse. BJUI. ,vol. 52, pp. 500- 505 ,(1980) , 10.1111/J.1464-410X.1980.TB03100.X
James A. Vafier, Nasser Javadpour, G.F. Worsham, Kevin J. O'Connell, Double blind comparison of T-antigen and ABO(H) cell surface antigens in bladder cancer Urology. ,vol. 23, pp. 348- 351 ,(1984) , 10.1016/0090-4295(84)90137-7
Heinz Baisch, Wolfgang Göhde, Walfried A. Linden, Analysis of PCP-data to determine the fraction of cells in the various phases of cell cycle. Radiation and Environmental Biophysics. ,vol. 12, pp. 31- 39 ,(1975) , 10.1007/BF02339807
Lars G. Collste, Marian Devonec, Zbigniew Darzynkiewicz, Frank Traganos, Thomas K. Sharpless, Willet F. Whitmore, Myron R. Melamed, Bladder cancer diagnosis by flow cytometry. Correlation between cell samples from biopsy and bladder irrigation fluid Cancer. ,vol. 45, pp. 2389- 2394 ,(1980) , 10.1002/1097-0142(19800501)45:9<2389::AID-CNCR2820450925>3.0.CO;2-Y