Macroporous alumina scaffolds consisting of highly microporous hollow filaments using three-dimensional ceramic/camphene-based co-extrusion

作者: Young-Wook Moon , Ik-Jun Choi , Young-Hag Koh , Hyoun-Ee Kim

DOI: 10.1016/J.JEURCERAMSOC.2015.08.017

关键词:

摘要: Abstract This study proposes a novel type of macroporous ceramic scaffolds, which are comprised hollow tubular filaments with highly microporous structure, using 3-dimensional ceramic/camphene-based co-extrusion (3D-CoEx). The use an initial feedrod, camphene core and alumina/camphene shell, enabled the construction frameworks micropores through removal phase. produced scaffolds showed 3-dimensionally interconnected macropores dimensions ∼250–300 μm × 400–550 μm, were surrounded by alumina (∼500 μm in diameter) featuring number (several tens microns size). unique macro/micro-porous structure could achieve combination both reasonably high compressive strength ∼5.4 MPa very porosity 86 vol%. In addition, final mechanical properties overall porous be fine-tuned adjusting content alumina/camphene.

参考文章(28)
Young-Wook Moon, Kwan-Ha Shin, Young-Hag Koh, Won-Young Choi, Hyoun-Ee Kim, Production of highly aligned porous alumina ceramics by extruding frozen alumina/camphene body Journal of The European Ceramic Society. ,vol. 31, pp. 1945- 1950 ,(2011) , 10.1016/J.JEURCERAMSOC.2011.04.033
Karin A. Hing, Bioceramic Bone Graft Substitutes: Influence of Porosity and Chemistry International Journal of Applied Ceramic Technology. ,vol. 2, pp. 184- 199 ,(2005) , 10.1111/J.1744-7402.2005.02020.X
Sarah Michna, Willie Wu, Jennifer A. Lewis, Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds Biomaterials. ,vol. 26, pp. 5632- 5639 ,(2005) , 10.1016/J.BIOMATERIALS.2005.02.040
T.-M.Gabriel Chu, David G. Orton, Scott J. Hollister, Stephen E. Feinberg, John W. Halloran, Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures Biomaterials. ,vol. 23, pp. 1283- 1293 ,(2002) , 10.1016/S0142-9612(01)00243-5
M Tamaddon, JT Czernuszka, The need for hierarchical scaffolds in bone tissue engineering Hard Tissue. ,vol. 2, ,(2013) , 10.13172/2050-2303-2-4-773
Young-Wook Moon, Kwan-Ha Shin, Young-Hag Koh, Hyun-Do Jung, Hyoun-Ee Kim, Three-dimensional Ceramic/Camphene-based Coextrusion for Unidirectionally Macrochanneled Alumina Ceramics with Controlled Porous Walls Journal of the American Ceramic Society. ,vol. 97, pp. 32- 34 ,(2014) , 10.1111/JACE.12634
F. Cristina Gomes Sousa, Julian R. G. Evans, Sintered Hydroxyapatite Latticework for Bone Substitute Journal of the American Ceramic Society. ,vol. 86, pp. 517- 519 ,(2003) , 10.1111/J.1151-2916.2003.TB03332.X
Qiang Fu, Eduardo Saiz, Antoni P. Tomsia, Direct ink writing of highly porous and strong glass scaffolds for load-bearing bone defects repair and regeneration Acta Biomaterialia. ,vol. 7, pp. 3547- 3554 ,(2011) , 10.1016/J.ACTBIO.2011.06.030
Lorna J. Gibson, Michael F. Ashby, Cellular Solids: Structure and Properties ,(1988)
Nahum Travitzky, Alexander Bonet, Benjamin Dermeik, Tobias Fey, Ina Filbert-Demut, Lorenz Schlier, Tobias Schlordt, Peter Greil, Additive Manufacturing of Ceramic‐Based Materials Advanced Engineering Materials. ,vol. 16, pp. 729- 754 ,(2014) , 10.1002/ADEM.201400097