Omic profiling for drug safety assessment: current trends and public–private partnerships

摘要: The drug development process is currently being hindered by non-optimal prediction of toxicity. Advances in molecular profiling approaches, such as transcriptomics, proteomics and metabolomics, offer the potential to provide a more comprehensive insight into toxicological effects than hitherto possible. These new technologies present their own challenges, however, particularly relation standardization assessment. focus this article on describing current trends concerning application omic approaches safety assessment, with specific emphasis role public-private partnerships advancing emerging arena.